ProactivMD Essentials Acne Treatment System

ProactivMD Essentials Acne Treatment System

ProactivMD® Essentials System

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Clear acne with the power of Rx, without a doctor’s visit!
After 30 years as a prescription-only acne-fighter, the clinically proven retinoid Adapalene takes center stage in our newest innovation – ProactivMD, the complete healthy skin regimen which includes cleansing, toning, hydration and sun protection, all in one easy-to-use system.


How to use your Essentials System

Maximize your results with Proactiv by following these simple steps


Quick Start Guide

We’ll walk you through, step by step…


Your First Six Weeks Using ProactivMD
A Week-by-Week Guide

It won't happen to everyone, but it is worth mentioning retinization, the adjustment period in which the skin becomes acclimated to Adapalene Gel. During this time skin may become red, flaky and irritated. It is HIGHLY RECOMMENDED that you use a moisturizer to help relieve symptoms of retinization which typically begin to subside around week 4 of your retinoid treatment.

You May Experience Retinization and it’s OK

Some, but not all users may experience dryness, redness, irritation - known as retinization -- while your skin adjusts to Adapalene Gel. The best defense is to generously hydrate with a moisturizer both day and night as part of your skincare regimen.

Retinization is a normal part of the process and side effects typically start to subside by Week 4.



Clear acne with the power of Rx, without a doctor’s visit. After 30 years as a prescription-only acne-fighter, the retinoid Adapalene takes center stage in our newest innovation – ProactivMD, the complete healthy skin regimen which includes cleansing, toning, hydration and sun protection, all in one easy-to-use, benzoyl peroxide-free system.


  • Cleans and gently exfoliates the skin with tiny exfoliating beads
  • Helps unclog pores and minimizes the appearance of pores
  • Helps balance the skin’s pH
  • Provides UVA/UVB protection
  • Helps control shine
  • First FDA-approved over-the-counter topical retinoid* for acne treatment
  • Dermatologist developed and tested

How to Use

ProactivMD is designed to be used consistently for best results.
DAILY AM & PM: Deep Cleansing Face Wash
Use twice daily, morning and night. Treat your whole face avoiding eye area. Apply a generous amount to dampened skin and gently massage with fingertips for 1-2 minutes. Rinse thoroughly with warm water.
DAILY AM & PM: Balancing Toner
Apply to cleansed skin with a cotton ball or pad in an upward motion, morning and night as needed, allowing Balancing Toner to dry before moving on to the next step. If irritation or sensitivity develops, discontinue use and consult a doctor.
DAILY AM: Daily Oil Control Moisturizer SPF 30
Apply to face and neck as needed. Can be used under makeup. Apply liberally prior to sun exposure. Reapply at least every 2 hours. Children under 6 months: ask a doctor.
DAILY PM: Adapalene Gel 0.1%
Adults and children 12 years of age and older: Use once daily. Clean the skin gently and pat dry before applying the product. Cover the entire affected area with a thin layer. Children under 12 years of age: ask a doctor.


Deep Cleansing Face Wash
Ingredients: water, cocamidopropyl betaine, distearyl phthalic acid amide, polyethylene, cetyl alcohol, stearyl alcohol, jojoba esters, ammonium laureth sulfate, camellia sinensis leaf extract, aloe barbadensis leaf juice, menthol, butylene glycol, PEG-120 methyl glucose dioleate, sodium hydroxide, disodium EDTA, phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben, fragrance, chromium hydroxide green.
Balancing Toner
Ingredients: water, hamamelis virginiana (witch hazel) water, polysorbate 20, aloe barbadensis leaf juice, rosa canina fruit extract, anthemis nobilis flower extract, hamamelis virginiana (witch hazel) leaf extract, panthenol, glycerin, hydroxyethylcellulose, sodium PCA, tetrasodium EDTA, benzoic acid, citric acid, benzophenone-4, imidazolidinyl urea, methylparaben, propylparaben, phenoxyethanol, fragrance, blue 1, yellow 5.
Daily Oil Control Moisturizer SPF 30

Active Ingredients: avobenzone 3%, octisalate 5%, octocrylene 7%

Inactive Ingredients: water, isopropyl lauroyl sarcosinate, glycerin, dimethicone, diisopropyl sebacate, polymethyl methacrylate, aluminum starch octenylsuccinate, sucrose tristearate, silica, pentylene glycol, polysorbate 61, dimethiconol, sodium stearoyl glutamate, phenoxyethanol, caprylyl glycol, tocopheryl acetate, glycyrrhetinic acid, panthenol, triethanolamine, allantoin, carbomer, potassium sorbate, zinc gluconate, xanthan gum, disodium EDTA, hydroxypalmitoyl sphinganine.

Adapalene Gel 0.1%

Active Ingredient: Adapalene 0.1% (retinoid)

Inactive Ingredients: carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water, sodium hydroxide.

May contain hydrochloric acid to adjust pH.

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